Blades fans who follow Chris Wilder's side on the road in the Premier League next season will amass close to 5,000 miles.
There will be five trips to the capital, with Crystal Palace's Selhurst Park the furthest away.
United will also face three games along the south coast, with Bournemouth, Brighton and Southampton the destinations.
The trip to Eddie Howe's Cherries, is the furthest the Blades will travel next term, clocking up 452 miles in the process.
The games at champions Manchester City and Manchester United are the only two games that are less than 100 miles away from S2.
|Brighton and Hove Albion||446|
|West Ham United||351|
*The figures, are the return mileage to each top-flight club, from and back to Bramall Lane.