United's 2018/19 Sky Bet Championship campaign will kick-off with a televised home clash against Swansea City.
The Swans, relegated from the top-flight last term, will visit Bramall Lane on Saturday 4th August, kick-off 5.30pm.
The first Steel City derby of the campaign will also take place at the Lane, with the Owls visiting in November, with the reversal fixture at Hillsborough in March.
Both Sheffield derbies will be immediately followed by clashes against Rotherham United, with a trip to the AESSEAL New York Stadium coming first.
Boxing Day sees the Blades welcome Frank Lampard's Derby County to S2, followed by another home game against Blackburn Rovers three days later, prior to a New Year's Day trip across the Pennines to Wigan Athletic.
On the final day of the season, Sunday 5th May 2019, United will face Gary Rowett's Stoke City at the bet365 Stadium.
Click here to download the fixtures to your phone, tablet or desktop to keep all the key dates on hand during the season - updated automatically from around 10am.