Chris Wilder expects Hull City to be 'fighting mad' for a result at the KCOM Stadium on Friday evening.
And the Blades boss knows his side will have to be at their best, to beat Nigel Adkins's Tigers.
Wilder commented: "I've been consistent in my respect for every team we've faced and the players in their building.
"I said after we'd beat Hull back in November that they have a squad full of internationals and some really good players.
"If they click on the day and say yes, they can win games of football, but they've had problems on and off the pitch and it doesn't seem a happy place.
"The opportunity on Friday for them to win a big game, is there for them as much as it is for us."
The manager added: "The position of Hull City means they know the prospect of dropping down to League One isn't a great one for anybody at the club and they will be fighting like mad to make sure that doesn't happen.
"They have the quality and Championship experience to win football matches though that's for sure, like QPR, they've got more Championship experience than us."