Speaking ahead of Tuesday's trip to Bolton, boss Chris Wilder believes his squad have the 'flexibility' to change their approach as and when it is necessary.
He remarked: "We have the ability and confidence to change, but we're set in a formation that suits us and has served us pretty well so far.
"But players, managers and coaches have to be adaptable. Our players are intelligent enough to grab something different if we have to change things and we have a flexibility in what we can do.
"We changed at times last year and we will need to again at times this season, but we have enough technical ability and tactical awareness to be able to drop into different roles.
"Good footballers have that ability and aren't set in their ways and we believe we have enough of that in the squad to make it happen."
Chris Basham is set for his 150th Blades start at the Macron Stadium on Tuesday and he got a glowing reference from his boss, who added: "Chris typifies what we're all about, he is a whole-hearted character who always gives 100% every time he plays and also during the week in training.
"He has a will to win, he is a big character in the dressing room, but he is also a very good player, that goes under the radar at times.
"He was outstanding at Sunderland, he is selfless and will do different jobs for the team if necessary. He has been fabulous to work with and deserved a new contract in the summer."