Chris Wilder said there was a 'bittersweet' taste following Friday's win at Burton Albion that saw the Blades go back to the top of the Championship.
United's 3-1 success at the Pirelli Stadium saw them leapfrog Wolves at the summit of the division, but it came at a big cost, with Paul Coutts suffering a suspected broken leg.
Speaking in the aftermath of the win over Nigel Clough's side, Wilder remarked: "It looks like Paul has broken his leg unfortunately. It's a penalty first and foremost, but the bigger issue is the leg break Paul appears to have suffered.
"It's a bittersweet taste really because we've produced an outstanding first-half performance against a side that have beaten some big teams at the Pirelli and one that has battled ever so hard to stay in the division for the last season and a bit.
"So to come to Burton and produce that performance and to see the game out to get the win that takes us to the top of the Championship again means we should be jumping through hoops, but we're not and out thoughts are with Paul."
Wilder added: "At half-time, we said he is a pal and an extremely talented player and the lads were there when it happened.
"But we're a committed side, we're competitive and we run about, so these things could happen and unfortunately it's happened to Paul, we can't change what we're about.
"I won't allow that to happen, we were flatter in the second-half but we thoroughly deserved the victory in the end."