Blades boss Nigel Adkins is demanding his players react in a positive manner to Tuesday's loss at home to Shrewsbury Town, when they face Barnsley at Oakwell on Saturday.
The Gaffer has called the weekend's South Yorkshire derby as an 'opportunity' to right the wrongs of the midweek disappointments against the Shrews and admits he will need to be 'ruthless' in ensuring United bounce back to form against the Tykes.
Adkins remarked: "The beauty of football is the next game is always just round the corner.
"When you have endured the disappointments of a such a defeat as we had the other night it presents an opportunity for the players to go back out there and show resilience, grit and determination to succeed.
"We have spoken to the players about the different scenarios that happened against Shrewsbury, but that game has been put to bed now and we must move on together.
"We can only affect the future and that's the next game, we will also have a large number of passionate Blades fans backing us all the way.
"I am up for the fight, the coaching staff are and we have to ensure the players mindset is right when they step across that white line on Saturday lunchtime."
The United manager added: "I have to be ruthless in terms of selection and tactics, we simply have to find solutions to get us winning football matches again.
"We have conceded too many goals and not won enough matches, so we have to improve and quickly.
"I am demanding of the players but we have to make sure we are giving our players the best possible opportunity to go out there and consistently win football matches."