Nigel Clough says securing United's participation in the end of season play-offs with a victory over Bradford City will help erase the memories of the disappointments from the midweek defeat against Yeovil Town.
Clough acknowledged the Blades were lacklustre during a performance that fell well below par in Somerset, although he is backing his players to respond positively against Phil Parkinson's side at the weekend.
But at the same time, the Gaffer is mindful that City themselves will be smarting, following a 6-0 home drubbing against champions-elect Bristol City on Tuesday evening.
Looking ahead, Clough remarked: "Saturday's game is a big one for us, especially after a very poor showing at Yeovil, but we remain in a very strong position within the play-off picture. If we win it puts a lot of pressure on the teams below us and that's all we can do, focus on ourselves.
"We know it was not good enough at Yeovil, the fans do too, but hopefully everyone will come to Bramall Lane optimistic and confident of a good result.
"But it won't be an easy game, despite Bradford's recent form. They have hit a bit of a wall of late, but like us, they have proved that on their day they can beat anybody, not just in this division, but also the likes of Chelsea and Sunderland.
"They come into the game on the back of a heavy defeat and like we expect from our players, Phil will be demanding the same from his, so a good start is a must for us because whoever gets their midweek loss out of their systems first will have a very good chance of winning the game on Saturday."