Nigel Clough says the players have been warned they can afford to take nothing for granted when the Blades return to Sky Bet League One action on Wednesday night.
Clough's men host Carlisle, looking for a tenth consecutive victory in all competitions following Sunday's victory over Charlton Athletic, but the Blades boss believes the Cumbrians will be keen to catch United off guard at Bramall Lane.
Looking ahead, Clough remarked: "I have no doubt that Carlisle will be thinking that we won't be at after Sunday, but we have to make sure it isn't a case of after the lord mayor's show.
"Graham Kavanagh will want to see his players get into our faces and play with a good tempo, but although we plan to make changes taking the forthcoming schedule into account, we will be competitive, the players have already been told of the dangers of Carlisle.
"They lost 2-1 at Port Vale on Saturday but they are scrapping for their lives and they will keen to try and put some daylight between themselves and the bottom four."
The Gaffer added: "We just the want this run to keep going and going though, that is our focus and if we can make it ten wins on the bounce that will be something else to be very proud of.
"At the moment we are just looking to get to the 50 points mark as soon as possible, from there who knows what is possible."