United's youngsters slipped to a disappointing defeat against Leeds United at Thorpe Arch, despite a goal from Danny Ramsey.
The Blades never really recovered from conceding twice in the opening half hour and despite Danny Ramsey's goal threatening a comeback, Leeds dominated thereafter and could even afford the luxury of missing a penalty in the second-half.
Coach Travis Binnion remarked: "Overall we were second best throughout, we played some excellent stuff early on, but once Leeds scored we lost our way and when we fell two goals behind it was always going to be difficult to turnaround.
"Ultimately poor defending and decision making in crucial areas proved to be our undoing."
Danny Ramsey and Kler Heh both wasted good opportunities in the opening exchanges and the Blades were punished in the 21st minute after mix up at the back allowed Leeds to take the lead.
The goal gave the hosts confidence and within seven minutes they had doubled their advantage, Ramsdale was powerless to stop a powerful drive on the angle.
United responded positively, only a dubious handball decision prevented Calvert-Lewin from halving the deficit, but the Blades managed to reduce the arrears before half-time.
In the very next attack, Cheeseman released Kedman whose pace got him on the outside of his marker, before he squared a perfect ball for RAMSEY to coolly slot home from just to the right of the penalty spot.
Kedman was proving a real threat and he could have leveled with the last kick of the half after good play involving Cockerline and Calvert-Lewin.
Unfortunately for the visitors, the second period was one-way traffic and it was the Blades that were on the receiving end, although with the aid of goal line technology Calvert-Lewin would have been credited with a stunning 25-yard strike that was clearly over the line.
At the other end, Adebowale was peanalised for an infringement in the box, but Leeds missed the resulting penalty, before making the game safe in the 79th minute. Poor defending allowed a free shot from 12 yards out, which went under the body of Ramsdale.
Graham Kelly and Kler Heh both had chances towards the end, but a revival was beyond the Blades.
Blades: Ramsdale, Ramsey (Wright 55), Kelly, Ishmail (Fixter 61), Adebowale, Cheeseman, Heh, Calvert-Lewin, Cockerline (Slew 55), Hinchliffe, Kedman.
Unused: Hallam, Parkin.