Blades boss David Weir felt his team were unfortunate to be defeated at Molineux on Saturday.
Second-half goals from Wolves duo Leigh Griffiths and Bakary Sako consigned the Blades to a sixth consecutive league loss, but Weir felt United's endeavors deserved some reward.
Speaking afterwards he said: "It is another defeat that is hard to take because I thought we put everything into the game.
"The lads effort and application, matched with our technical play in the first-half was very good, but again it is another hard luck story.
"It is hard to remain positive but we have to. In the first-half it is the best we have played this season.
"We controlled the game, passed the ball and created opportunities to get ourselves in front but it wasn't to be."
The Gaffer added: "We opened Wolves up and we made Carl (Ikeme) work but you have to take those chances to win matches.
"We were frustrated at half-time because we knew we had seen enough of the ball to be in front.
"The quality Wolves have at their disposal was demonstrated with Sako's contribution to both their goals.
"It was a tremendous cross to Leigh (Griffiths) and his shot at the end was unstoppable."