Danny Wilson insists his players will be ready for the challenge of playing at Huish Park on Saturday.
Renowned as one of the toughest places to visit in League One, the Blades boss is keen to emulate the victory at Yeovil Town last season, when Chris Porter's header settled a closely-fought contest.
"We had a great victory there last season and at the weekend our aim is to replicate that success," said Wilson. "It is a very tight stadium, the crowd feels like it is on top of you and that makes for a fantastic atmosphere. It is such a tight pitch that you can soon get from one end of the field to the other.
"They get a lot of success from keeping the pressure on the opposition so our concentration levels must be spot on and we must demonstrate a high level of resilience.
"We will have to roll our sleeves up and defend properly, as we did against Doncaster, but going forward I feel we have players who can help us bring all three points back to Sheffield."
Wilson, though, was keen to acknowledge that nothing should be taken for granted in Somerset: "Yeovil got off to a flying start and were soon top of the league, that has tailed off of late and they have lost a couple of matches, but at home they are a strong outfit.
"Our travelling support was brilliant there last season, but they will also know how difficult it was to get all three points and this weekend will be no different, it will be a real battle, but one we are up for.