United's U23s will play the majority of their competitive fixtures at Chesterfield's Proact Stadium during the 2019/20 campaign.
The two clubs have agreed a deal, for United's oldest development age group to use the Spireites Derbyshire home with games scheduled to be played on a Monday whenever possible.
Season ticket holders of both clubs will be admitted free of charge.
Chris Wilder is also expected to take a full strength first-team squad to face John Sheridan's side in a pre-season friendly at the venue on Tuesday 23rd July, kick-off 7.30pm.
As per recent years, there remains the possibility of switching games to be played at Bramall Lane and also United's Shirecliffe training base.