The majestic talent of Thierry Henry engineered Arsenal's 3-0 victory and ruined Neil Warnock's 1,000 League game as a manager back in September 2006.
United's much-changed team could have been applauded for keeping Henry and Arsenal quiet for more than an hour of the Premiership encounter at the new Emirates Stadium, before Arsene Wenger's league of nations turned their pressure into goals.
All of Arsenal's strikes came in a 16-minute second half spell with the names of William Gallas, Phil Jagielka (own goal) and Henry on the scoresheet.
Arsenal: Lehmann, Fabregas, Toure, Rosicky (Hleb 71), Ljungberg (Baptista 78), Gallas, Henry, Gilberto, Djourou, Adebayor (Van Persie 71), Eboue.
Unused: Flamini, Almunia.
Blades: Bennett, Davis, Jagielka, Hulse, Sommeil (A. Quinn 78), Gillespie, Armstrong, Leigertwood, Wright, Geary (Kozluk 78), Kazim-Richards (Kabba 89).
Unused: Bromby, Akinbiyi.
Bookings: Eboue, Fabregas (Arsenal) Hulse (Blades)
Attendance: 59,912
Referee: A Wiley